Figure 1: Arbovirus replication cycle in mosquito. A) Mosquito takes the blood meal from an infected host. Immune host cell (monocytes, macrophages and dendritic cells) are the first target during the infection in mammals. B) The viral particles enter to the midgut and replicate. C) Later, pass into the hemolymph and infect the fat body cells, trachea, hemocytes, ovaries, nerve tissue, and salivary glands, spreading the infection to the entire insect. D) Finally, the infection is spread through the saliva to another naive host. This figure was created with BioRender.com.