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Early virus clearance of SARS-CoV-2 among co-infection with malaria

 B.Y.L. Nair Charitable Hospital and Topiwala National Medical College, Mumbai, 400008, Maharashtra

Correspondence Address:
Niraj N Mahajan,
Department of Obstetrics and Gynecology, B.Y.L. Nair Charitable Hospital and T. N. Medical College, Mumbai-400008

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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0972-9062.364758

Background & objectives: India has witnessed significant number of cases of co-infection of malaria or dengue with COVID-19, especially during monsoon season. It has been speculated that anti-malarial immunity might have a protective role in co-infection. Retrospective analysis of co-infection of vector borne diseases with COVID-19 was done for comparing their remission with matched controls with COVID-19 by means of epidemiological data. Methods: Medical case records of patients with Co-infection of Malaria or dengue with COVID-19 admitted at TNMC and BYL Nair Charitable Hospital, Mumbai the first dedicated COVID-19 hospital in India, from 1st March 2020 to 31st October 2020 were analyzed retrospectively. Out of 91 cases of co-infection of SARS-CoV-2 infection with vector-borne diseases, virus clearance (VC) analysis was done for 61 co-infections with malaria. Results: Median duration of VC for co-infection with malaria was 8 days whereas, it was 12 days for controls with COVID-19 (p=0.056). Young patients (≤50 years) with co-infection recovered faster than controls age (p=0.018). Interpretation & conclusion: Co-infection with malaria is associated with less severe disease and early recovery in the form of early VC. Genetic and immunological studies are necessary to confirm malaria protection against SARS-CoV-2 infection.

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