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Biosensor-based methods for Crimean-Congo hemorrhagic fever Virus detection


1 Department of Virology, School of Public Health; Research Center for Clinical Virology, Tehran University of Medical Sciences, Tehran, Iran
2 Department of Biochemistry, Faculty of Sciences, Payame Noor University; Virology Department, Pasteur Institute of Tehran, Tehran, Iran
3 Microbial Biotechnology Research Center, Department of Microbiology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
4 Neuroscience and Addiction Studies Department, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran
5 Abadan University of Medical Sciences, Iran

Correspondence Address:
Samaneh Abbasi,
Abadan University of Medical Sciences
Iran
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0972-9062.328976

Crimean-Congo hemorrhagic fever is a tick-borne disease with high fatality rate that is endemic in some parts of Asia, Africa and Europe. Rapid diagnostics of crimean-congo hemorrhagic fever is necessary for appropriate clinical management of this disease and also can be useful in preventing of secondary spread from human-to-human , though, common tests which are used to diagnose crimean-congo hemorrhagic fever have some limitations. Here we review 1) Common diagnostic tests for CCHF, 2) a review on limitations in laboratories methods of CCHF and 3) a literature review on biosensor researches for detection of CCHF. It is necessary to design and develop an effective, rapid, and also low-cost tool such as biosensor to detect crimean-congo hemorrhagic fever. Base on the key role of rapid detection of CCHF in the control of infection, development of a biosensor as a rapid tool seems very major in the diagnosis of CCHF, though, there are limited studies on this field and more researches are needed in this issue.


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