|LETTER TO THE EDITOR
|Year : 2021 | Volume
| Issue : 2 | Page : 181
Concurrent Zika virus infection and tuberculosis: An estimated incidence in endemic tropical country
Beuy Joob1, Viroj Wiwanitkit2
1 Sanitation 1 Medical Academic Center, Bangkok, Thailand
2 Dr DY Patil University, Pune, India, Hainan Medical University, China, Faculty of Medicine, University of Nis, Serbia, Joseph Ayobabalola University, Ikeji-Arakeji, Nigeria, Chulalongkorn University, Bangkok, Thailand
|Date of Submission||03-Sep-2019|
|Date of Acceptance||30-Jun-2020|
|Date of Web Publication||13-Jan-2022|
Sanitation 1 Medical Academic Center, Bangkok
Source of Support: None, Conflict of Interest: None
|How to cite this article:|
Joob B, Wiwanitkit V. Concurrent Zika virus infection and tuberculosis: An estimated incidence in endemic tropical country. J Vector Borne Dis 2021;58:181
|How to cite this URL:|
Joob B, Wiwanitkit V. Concurrent Zika virus infection and tuberculosis: An estimated incidence in endemic tropical country. J Vector Borne Dis [serial online] 2021 [cited 2022 Jan 26];58:181. Available from: https://www.jvbd.org/text.asp?2021/58/2/181/331417
Mosquito-borne arbovirus infection is an important group of infectious diseases. The disease is common in many developing countries. In the same area, there are also other common infections such as tuberculosis. There is a possibility that the concurrence between arbovirus infection and tuberculosis can occur. Nevertheless, the occurrence might be rare. In our recent report, the situation of concurrence between dengue and tuberculosis in Thailand, a tropical country in Indochina was analyzed and it could show that there is a possibility but it is extremely rare. Here, the authors would like to specifically discuss the possibility of concurrent Zika virus infection and tuberculosis. The estimation was performed using the same technique, jointed probability analysis, as used in the previous report. The setting is Thailand, a tropical country where both tuberculosis and Zika virus infection are detectable.
The reported incidence of dengue in Thailand is equal to tuberculosis in Thailand i.e. equal to 171/100,000 population while the reported incidence of Zika virus infection is equal to 3.83/100,000 population. Based on mathematical modeling analysis, the estimated incidence of concurrent Zika virus infection and tuberculosis will be equal to 0.06.5493 per 1,000,000 population. This rate is extremely lower than the previously reported in case of concurrence between dengue and tuberculosis.
Of interest, although Zika virus has already been reported in several countries around the world within the past few years, there has never been any report on Zika virus infection among tuberculosis patients despite the disease occuring in many countries where tuberculosis is also common. The result from the present clinical mathematical model analysis can explain the lack of observed concurrence between Zika virus infection and tuberculosis. Nevertheless, both Zika virus infection and tuberculosis also share a common immunopathogenesis mechanism via inflammosome stimulation,. The competitive biological process might occur in case that there is concurrence between two infection, leading to difficulty in co-occurrence. Further studies on this specific aspect of interrelationship between Zika virus infection and tuberculosis is recommended
Conflict of interest: None
| References|| |
Joob B, Wiwanitkit V. Concurrent dengue and tuberculosis: An estimated incidence in endemic tropical country and explanation for low observed incidence. Biomed Biotechnol Res J
Pornpattkul W. Zika virus infection and disease situation in Nonthaburi. Thai J Prev Med Soc
2017; 7: 244–50.
Amaral EP, Riteau N, Moayeri M, Maier N, Mayer-Barber KD, Pereira R, et al
. Lysosomal Cathepsin Release Is Required for NLRP3-Inflammasome Activation by Mycobacterium tuberculosis in Infected Macrophages. Front Immunol
2018 Jun 21; 9: 1427.
Wang W, Li G, De Wu, Luo Z, Pan P, Tian M, et al
. Zika virus infection induces host inflammatory responses by facilitating NLRP3 inflammasome assembly and interleukin-1β secretion. Nat Commun
2018 Jan 9; 9(1): 106.