Chagas’ disease among school students from Chiapas, Mexico: Two cases of Chagasic cardiomyopathy

Vidal-López Dolores Guadalupe; Bucio Torres Martha; Cabrera Bravo Margarita; Torres Gutiérrez Elia; Schlie-Guzmán María Adelina; Pérez-Vargas Adrián; Salazar-Schettino Paz María

doi:10.4103/0972-9062.325639

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RESEARCH ARTICLE

Year : 2021 | Volume : 58 | Issue : 2 | Page : 148-153

Chagas’ disease among school students from Chiapas, Mexico: Two cases of Chagasic cardiomyopathy

Vidal-López Dolores Guadalupe¹, Bucio Torres Martha², Cabrera Bravo Margarita², Torres Gutiérrez Elia², Schlie-Guzmán María Adelina¹, Pérez-Vargas Adrián³, Salazar-Schettino Paz María¹
¹ Instituto de Ciencias Biológicas, UNICACH, Chiapas, Mexico
² Laboratorio de Biología de Parásitos, Facultad de Medicina, UNAM, Mexico City, Mexico
³ Facultad de Medicina, UNACH, Chiapas, Mexico

Correspondence Address:
Dr Salazar-Schettino Paz María
Laboratorio de Biología de Parásitos, Edificio A, 2° piso, Facultad de Medicina, Circuito Interior, Ciudad Universitaria, Avenida Universidad 3000, Ciudad de México, México. C.P. 04510
Mexico
Torres Gutiérrez Elia
Laboratorio de Biología de Parásitos, Edificio A, 2° piso, Facultad de Medicina, Circuito Interior, Ciudad Universitaria, Avenida Universidad 3000, Ciudad de México, México. C.P. 04510
Mexico

Source of Support: None, Conflict of Interest: None

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DOI: 10.4103/0972-9062.325639

Background & objectives: Chagas disease is a vector-borne life-threatening illness originally confined to the Americas. Seroprevalence studies have been reported in the Mexican state of Chiapas; nevertheless, no clinical/cardiological studies have been conducted to detect underage cases. The aim of the present work was to detect underage cases in the Mexican state of Chiapas. Methods: A serological screening by ELISA was conducted on 1556 blood samples from school pupils; seropositiv- ity was confirmed by indirect ELISA and indirect immunofluorescence. Seropositive cases were clinically assessed in a hospital, and electrocardiographic and echocardiographic studies were performed. Descriptive statistics were used for analysis. Results: Seropositivity was confirmed in three cases in the population under study (0.19%). Cardiological studies confirmed the presence of alterations associated to Chagasic cardiomyopathy in two of the three patients. Interpretation & conclusion: The conditions for an active transmission of T. cruzi infection are met in the rural localities under study. Additionally, the presence of Chagasic cardiomyopathy in underage patients highlights the relevance of an early detection of cases to provide specific treatment at the onset of the infection and to implement epidemiological surveillance as suggested by PAHO/WHO.

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