| REVIEW ARTICLE |
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| Year : 2013 | Volume
: 50
| Issue : 3 | Page : 155-162 |
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Drug targets for lymphatic filariasis: A bioinformatics approach
Om Prakash Sharma, Yellamandaya Vadlamudi, Arun Gupta Kota, Vikrant Kumar Sinha, Muthuvel Suresh Kumar
Centre for Bioinformatics, School of Life Science, Pondicherry University, Puducherry, India
Correspondence Address:
Muthuvel Suresh Kumar
Assistant Professor, Department of Bioinformatics, Centre for Bioinformatics, School of Life Science, Pondicherry University, Puducherry–605 014
India
 Source of Support: None, Conflict of Interest: None  | Check |
PMID: 24220073 
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This review article discusses the current scenario of the national and international burden due to lymphatic filariasis (LF) and describes the active elimination programmes for LF and their achievements to eradicate this most debilitating disease from the earth. Since, bioinformatics is a rapidly growing field of biological study, and it has an increasingly significant role in various fields of biology. We have reviewed its leading involvement in the filarial research using different approaches of bioinformatics and have summarized available existing drugs and their targets to re-examine and to keep away from the resisting conditions. Moreover, some of the novel drug targets have been assembled for further study to design fresh and better pharmacological therapeutics. Various bioinformatics-based web resources, and databases have been discussed, which may enrich the filarial research. |
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